I started sermorelin 12 weeks ago through my doctor mostly hoping for better recovery, but the unexpected headline has been sleep. My wearable used to show me getting 25 to 35 minutes of deep sleep a night. The last month I'm consistently in the 70 to 90 minute range. I wake up before my alarm feeling actually rested, which has not happened in years. Nothing else in my routine changed. Same bedtime, same caffeine cutoff, same training. Anyone else find the sleep effect showed up before anything else?
Week 8 check-in. The clearest change for me is recovery. I used to need a full 3 days before I could hit legs hard again. Now I'm fine in about 2, and the deep soreness that used to linger is mostly gone. Strength is creeping up too, but I think that's downstream of just being able to train more often without feeling beat up. Sleep is better, which probably feeds the recovery as well. Logging it here so I have a record to look back on.
Got my follow-up labs back. Sharing because hard numbers are more useful than vibes. Baseline IGF-1 was on the low end of the reference range for my age. After 12 weeks on sermorelin my IGF-1 moved up meaningfully and is now comfortably mid-range. My doctor was happy with the trend and we're holding the current protocol. If you're going to do this, get baseline bloodwork first. You cannot interpret a follow-up number without it. Talk to your physician about what to test and how often.
I came into this expecting recovery and sleep benefits. What surprised me was the daytime energy and mental clarity. Around week 5 the afternoon slump I'd fought for years just sort of faded. Hard to say how much is direct versus a downstream effect of finally sleeping well. Either way, my focus at work is the best it's been in a long time. Anyone else notice cognitive or energy changes they weren't anticipating?
Not the reason I started, but a welcome surprise. Around month 3 my wife pointed out my skin looked better, and I do think it's a little firmer and more hydrated looking. My hair feels a bit thicker too, though that's harder to judge. I know GH plays a role in collagen and skin, so it's plausible rather than just placebo. Anyone else notice changes here? Trying to figure out what's real versus wishful thinking.
Data nerd post. I've been logging sleep stages with a ring since well before starting sermorelin, so I have a clean baseline. The 30-day average before: deep sleep around 11 percent of total, lots of fragmented nights. The 30-day average now, about 9 weeks in: deep sleep around 18 percent, far fewer wakeups, and my resting heart rate dropped a few beats. REM is roughly the same. N of 1 and not controlled, but the deep-sleep shift is the most consistent signal in my data. Happy to share how I'm tracking if useful.
Half a year in, so here's the honest full picture, good and modest. Sleep: the biggest and most reliable change, dramatically more deep sleep. Recovery: clearly faster between hard sessions. Body composition: a gradual recomposition, leaner midsection and a bit more muscle, but slow and unglamorous, not a dramatic before/after. Energy and mood: noticeably better, likely tied to the sleep. Things I'd tell my past self: get baseline labs, go through a real provider, be patient, and keep your training and nutrition dialed because the peptide amplifies good habits rather than replacing them.
Sermorelin vs CJC-1295, what made you choose one?
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Bloodwork update: IGF-1 levels after 12 weeks
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